A blast of HOTAIR silences distant chromatin
نویسندگان
چکیده
منابع مشابه
Nucleosome-free DNA regions differentially affect distant communication in chromatin
Communication between distantly spaced genomic regions is one of the key features of gene regulation in eukaryotes. Chromatin per se can stimulate efficient enhancer-promoter communication (EPC); however, the role of chromatin structure and dynamics in this process remains poorly understood. Here we show that nucleosome spacing and the presence of nucleosome-free DNA regions can modulate chroma...
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ژورنال
عنوان ژورنال: Nature Reviews Genetics
سال: 2007
ISSN: 1471-0056,1471-0064
DOI: 10.1038/nrg2174